How many employees work at Spruce Biosciences?
Spruce Biosciences, Inc. (SPRB) has approximately 8 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Spruce Biosciences’s total headcount has declined 57.8% from 19 employees in 2023 to 8 in 2026.
Is Spruce Biosciences hiring right now?
No, Spruce Biosciences is not actively hiring. Spruce Biosciences had 0 active job postings in 2026, a 0.0% no change from 2025 — see job openings & hiring trends.
About Spruce Biosciences’s Workforce
Spruce Biosciences, Inc. (SPRB) is a Pharmaceuticals company that employs 8 people worldwide as of March 2026. It is the 8th-largest by headcount among its peers. Founded in 2014, the company is headquartered in South San Francisco, California and trades on the NASDAQ.
Spruce Biosciences's workforce has declined 57.8% from 2023 to 2026, down 23.9% year over year in 2026. It fell to a low of 8 in 2025 Q4 before recovering. Its workforce is concentrated most in North America (100.0%).
Spruce Biosciences's functional groups are Finance and Operations (55.5%), Engineering (33.7%), and Sales and Marketing (10.9%), with Engineering growing fastest (up 17.4%). The average salary is $299,383, highest in North America at a median of $264,000, up 27.5% year over year in 2026.
Spruce Biosciences's hiring activity held steady in 2026. Overall employee sentiment is negative and broadly stable.
Sourced from Revelio Labs workforce data.
- Ticker
- NASDAQ: SPRB
- Headquarters
- South San Francisco, California
- Founded
- 2014
- Industry
- Pharmaceuticals
- Employees
- 8
- YoY
- -23.9% (-4)
As of March 2026
Spruce Biosciences workforce metrics
Unlock hiring rate, attrition rate, and 12 additional workforce metrics for Spruce Biosciences. Compare to peers, export the dataset, and access the full quarterly history.
Unlock MetricsSpruce Biosciences Annual Employee Count (2023-2026)
- Spruce Biosciences had 8 employees in 2026, a 23.9% decline (-4) from 2025.
- Spruce Biosciences had 8 employees in 2025, a 34.6% decline (-5) from 2024.
- Spruce Biosciences had 13 employees in 2024, a 15.3% decline (-5) from 2023.
- Spruce Biosciences had 18 employees in 2023, a 7.8% decline from 2022.
Spruce Biosciences's total workforce has declined from 19 employees in 2023 to 8 in 2026.
Spruce Biosciences, Inc. quarterly employee count
| Year | Qtr | Employees | YoY Change | YoY % |
|---|---|---|---|---|
| 2026 | Q1 | 8 | -4 | -23.9% |
| 2025 | Q4 | 8 | -5 | -34.6% |
| 2025 | Q3 | 8 | -4 | -35.4% |
| 2025 | Q2 | 9 | -4 | -37.4% |
| 2025 | Q1 | 12 | -2 | -12.1% |
| 2024 | Q4 | 13 | -5 | -15.3% |
| 2024 | Q3 | 12 | -6 | -12.3% |
| 2024 | Q2 | 13 | -6 | -14.7% |
| 2024 | Q1 | 14 | -5 | -16.8% |
| 2023 | Q4 | 18 | +0 | -7.8% |
| 2023 | Q3 | 18 | +4 | -1.9% |
| 2023 | Q2 | 19 | +7 | +3.9% |
See Spruce Biosciences's complete headcount history, including quarterly breakdowns.
Get the DataSpruce Biosciences Employee Count by Region (2026)
North America accounts for the largest share of Spruce Biosciences's global workforce with approximately 100% of total employees.
Spruce Biosciences employees by region
| Region | Employees | % of Total |
|---|---|---|
| North America | 8 | 100.0% |
Drill into city-level data, hiring trends by region, and historic geographic shifts.
Unlock Geographic DataSpruce Biosciences Employee Count by Department (2026)
Spruce Biosciences's employee groups are Finance and Operations (55.5%), Engineering (33.7%), and Sales and Marketing (10.9%).
Spruce Biosciences employees by department
| Department | Employees | % of Total |
|---|---|---|
| Finance and Operations | 4 | 55.5% |
| Engineering | 3 | 33.7% |
| Sales and Marketing | 1 | 10.9% |
Compare Spruce Biosciences's department mix to industry peers.
See Full DataSpruce Biosciences Employee Salary by Region (2026)
Spruce Biosciences's average employee salary is $299,383 globally. Employees in North America receive the highest compensation.
Spruce Biosciences median employee salary by region (USD)
| Region | Median Salary |
|---|---|
| North America | $264,000 |
Unlock salary by role, level, and city — and compare to Spruce Biosciences's industry peers.
Unlock Salary DataSpruce Biosciences Job Openings and Hiring Trends (2023-2026)
- Spruce Biosciences had 0 active job postings in 2026, a 0% no change from 2025.
- Spruce Biosciences had 0 active job postings in 2025, a 0% no change from 2024.
- Spruce Biosciences had 0 active job postings in 2024, a 0% no change from 2023.
- Spruce Biosciences had 0 active job postings in 2023, a 0% no change from 2022.
- Hiring velocity in 2026: 0 new roles/month, up from 0 in 2025 and 0 in 2024.
Spruce Biosciences's hiring activity held steady in 2026.
Track new postings per month, role-level demand, and hiring velocity vs. peers.
Unlock Hiring DataSpruce Biosciences Employee Sentiment (2026)
Revelio Labs tracks employee sentiment across Spruce Biosciences's workforce based on public professional data. Overall sentiment is negative and has held steady year over year in 2026.
Overall
Unlock the full sentiment breakdown by department, tenure, and trend over time.
Unlock SentimentSimilar Companies
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Frequently Asked Questions About Spruce Biosciences
- How fast is Spruce Biosciences growing?
- In 2026, Spruce Biosciences's headcount shrank 23.9% to 8 employees, down from 12 in 2025.
- See the full headcount history
- Where are Spruce Biosciences employees located?
- Most Spruce Biosciences employees are based in North America (100.0% of headcount).
- Explore where the workforce is based
- What is the average salary at Spruce Biosciences?
- The average employee salary at Spruce Biosciences is approximately $299.4k per year.
- Analyze the salary distribution
- How many new job postings does Spruce Biosciences open per year?
- In Q1 2026, Spruce Biosciences opened 0 new job postings. In 2025, Spruce Biosciences opened 0 new job postings — about 0 per month.
- Track hiring trends by role
- When was Spruce Biosciences founded and where is it headquartered?
- Spruce Biosciences was founded in 2014 and is headquartered in South San Francisco, California.
- Compare Spruce Biosciences to industry peers
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