NASDAQ: XLO

How many employees work at Xilio Therapeutics?

Xilio Therapeutics, Inc. (XLO) has approximately 79 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Xilio Therapeutics’s total headcount has grown 5.1% from 76 employees in 2023 to 79 in 2026.

Data source: Revelio LabsCoverage: Global workforce, 20232026Published August 2026

Is Xilio Therapeutics hiring right now?

No, Xilio Therapeutics is not actively hiring. Xilio Therapeutics had 0 active job postings in 2026, a 200.0% decline from 2025 see job openings & hiring trends.

About Xilio Therapeutics’s Workforce

Xilio Therapeutics, Inc. (XLO) is a Pharmaceuticals company that employs 79 people worldwide as of March 2026. It is the 3rd-largest by headcount among its peers. Founded in 2015, the company is headquartered in Waltham, Massachusetts and trades on the NASDAQ.

Xilio Therapeutics's workforce has grown 5.1% from 2023 to 2026, up 13.2% year over year in 2026. It fell to a low of 55 in 2024 Q2 before recovering. Its workforce is concentrated most in North America (99.2%), followed by Eastern Europe (0.8%).

Xilio Therapeutics's functional groups are Engineering (39.2%), Finance and Operations (38.4%), and Sales and Marketing (22.4%), with Engineering growing fastest (up 13.8%). The average salary is $205,011, highest in North America at a median of $184,000, down 9.6% year over year in 2026.

Xilio Therapeutics's active job postings fell 200.0% in 2026 to 0, with new postings per month cooling from 2 in 2023 to 0 in 2026. Overall employee sentiment is neutral and broadly stable.

Sourced from Revelio Labs workforce data.

Ticker
NASDAQ: XLO
Headquarters
Waltham, Massachusetts
Founded
2015
Industry
Pharmaceuticals
Employees
79
YoY
+13.2% (+18)

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Xilio Therapeutics Annual Employee Count (2023-2026)

Interactive chart of Xilio Therapeutics annual worldwide employee count from 2023 to 2026.
  • Xilio Therapeutics had 79 employees in 2026, a 13.2% increase (+18) from 2025.
  • Xilio Therapeutics had 76 employees in 2025, a 11.6% increase (+16) from 2024.
  • Xilio Therapeutics had 60 employees in 2024, a 6.5% decline (-8) from 2023.
  • Xilio Therapeutics had 68 employees in 2023, a 9.8% decline (-24) from 2022.

Xilio Therapeutics's total workforce has grown from 76 employees in 2023 to 79 in 2026.

Xilio Therapeutics, Inc. quarterly employee count

YearQtrEmployeesYoY ChangeYoY %
2026Q179+18+13.2%
2025Q476+16+11.6%
2025Q373+15+11.3%
2025Q270+15+9.1%
2025Q161-2-3.1%
2024Q460-8-6.5%
2024Q358-12-5.6%
2024Q255-21-11.3%
2024Q163-21-10.8%
2023Q468-24-9.8%
2023Q370-20-12.1%
2023Q276-7-9.3%

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Xilio Therapeutics Employee Count by Region (2026)

North America accounts for the largest share of Xilio Therapeutics's global workforce with approximately 99% of total employees, followed by Eastern Europe.

Xilio Therapeutics employees by region

RegionEmployees% of Total
North America7899.2%
Eastern Europe10.8%

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Xilio Therapeutics Employee Count by Department (2026)

Xilio Therapeutics's employee groups are Engineering (39.2%), Finance and Operations (38.4%), and Sales and Marketing (22.4%).

Xilio Therapeutics employees by department

DepartmentEmployees% of Total
Engineering3139.2%
Finance and Operations3038.4%
Sales and Marketing1822.4%

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Xilio Therapeutics Employee Salary by Region (2026)

Xilio Therapeutics's average employee salary is $205,011 globally. Employees in North America receive the highest compensation.

Xilio Therapeutics median employee salary by region (USD)

RegionMedian Salary
North America$184,000

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Xilio Therapeutics Job Openings and Hiring Trends (2023-2026)

Interactive chart of Xilio Therapeutics annual active job postings from 2023 to 2026.
  • Xilio Therapeutics had 0 active job postings in 2026, a 200.0% decline (-1) from 2025.
  • Xilio Therapeutics had 1 active job postings in 2025, a 150.0% decline (-6) from 2024.
  • Xilio Therapeutics had 7 active job postings in 2024, a 111.1% increase (+5) from 2023.
  • Xilio Therapeutics had 2 active job postings in 2023, a 85.7% decline from 2022.
  • Hiring velocity in 2026: 0 new roles/month, down from 2 in 2025 and 2 in 2024.

Xilio Therapeutics's hiring is slowing: active job postings fell 200.0% in 2026 to 0, with new postings per month cooling from 2 in 2023 to 0 in 2026.

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Xilio Therapeutics Employee Sentiment (2026)

Revelio Labs tracks employee sentiment across Xilio Therapeutics's workforce based on public professional data. Overall sentiment is neutral and has held steady year over year in 2026.

Overall

NegativePositive

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Frequently Asked Questions About Xilio Therapeutics

How fast is Xilio Therapeutics growing?
In 2026, Xilio Therapeutics's headcount grew 13.2% to 79 employees, up from 61 in 2025.
See the full headcount history
Where are Xilio Therapeutics employees located?
Most Xilio Therapeutics employees are based in North America (99.2% of headcount), followed by Eastern Europe.
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What is the average salary at Xilio Therapeutics?
The average employee salary at Xilio Therapeutics is approximately $205k per year.
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How many new job postings does Xilio Therapeutics open per year?
In Q1 2026, Xilio Therapeutics opened 0 new job postings. In 2025, Xilio Therapeutics opened 26 new job postings — about 2 per month.
Track hiring trends by role
When was Xilio Therapeutics founded and where is it headquartered?
Xilio Therapeutics was founded in 2015 and is headquartered in Waltham, Massachusetts.
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