How many employees work at Septerna?
Septerna, Inc. (SEPN) has approximately 137 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Septerna’s total headcount has grown 121.6% from 62 employees in 2023 to 137 in 2026.
Is Septerna hiring right now?
Yes, Septerna is actively hiring. Septerna had 16 active job postings in 2026, a 13.3% increase from 2025 — see job openings & hiring trends.
About Septerna’s Workforce
Septerna, Inc. (SEPN) is a Biotech and Healthcare Services company that employs 137 people worldwide as of March 2026. It is the 8th-largest by headcount among its peers. Founded in 2019, the company is headquartered in South San Francisco, California and trades on the NASDAQ.
Septerna's workforce has grown 121.6% from 2023 to 2026, up 6.4% year over year in 2026. Its workforce is concentrated most in North America (98.2%), followed by Southern Europe (1.8%).
Septerna's functional groups are Finance and Operations (40.8%), Engineering (39.0%), and Sales and Marketing (20.2%), with Sales and Marketing growing fastest (up 21.3%). The average salary is $203,614, highest in North America at a median of $160,000, up 2.0% year over year in 2026.
Septerna's active job postings rose 13.3% in 2026 to 16, with new postings per month climbing from 4 in 2023 to 10 in 2026. Overall employee sentiment is positive and broadly stable.
Sourced from Revelio Labs workforce data.
- Ticker
- NASDAQ: SEPN
- Headquarters
- South San Francisco, California
- Founded
- 2019
- Industry
- Biotech and Healthcare Services
- Employees
- 137
- YoY
- +6.4% (+43)
As of March 2026
Septerna workforce metrics
Unlock hiring rate, attrition rate, and 12 additional workforce metrics for Septerna. Compare to peers, export the dataset, and access the full quarterly history.
Unlock MetricsSepterna Annual Employee Count (2023-2026)
- Septerna had 137 employees in 2026, a 6.4% increase (+43) from 2025.
- Septerna had 129 employees in 2025, a 4.3% increase (+38) from 2024.
- Septerna had 91 employees in 2024, a 7.5% increase (+22) from 2023.
- Septerna had 69 employees in 2023, a 0.3% increase (+13) from 2022.
Septerna's total workforce has grown from 62 employees in 2023 to 137 in 2026.
Septerna, Inc. quarterly employee count
| Year | Qtr | Employees | YoY Change | YoY % |
|---|---|---|---|---|
| 2026 | Q1 | 137 | +43 | +6.4% |
| 2025 | Q4 | 129 | +38 | +4.3% |
| 2025 | Q3 | 124 | +43 | +6.7% |
| 2025 | Q2 | 110 | +24 | +6.0% |
| 2025 | Q1 | 94 | +20 | +4.3% |
| 2024 | Q4 | 91 | +22 | +7.5% |
| 2024 | Q3 | 81 | +15 | +3.8% |
| 2024 | Q2 | 86 | +24 | +4.0% |
| 2024 | Q1 | 74 | +15 | +3.9% |
| 2023 | Q4 | 69 | +13 | +0.3% |
| 2023 | Q3 | 66 | +12 | +0.7% |
| 2023 | Q2 | 62 | +14 | +2.2% |
See Septerna's complete headcount history, including quarterly breakdowns.
Get the DataSepterna Employee Count by Region (2026)
North America accounts for the largest share of Septerna's global workforce with approximately 98% of total employees, followed by Southern Europe.
Septerna employees by region
| Region | Employees | % of Total |
|---|---|---|
| North America | 130 | 98.2% |
| Southern Europe | 2 | 1.8% |
Drill into city-level data, hiring trends by region, and historic geographic shifts.
Unlock Geographic DataSepterna Employee Count by Department (2026)
Septerna's employee groups are Finance and Operations (40.8%), Engineering (39.0%), and Sales and Marketing (20.2%).
Septerna employees by department
| Department | Employees | % of Total |
|---|---|---|
| Finance and Operations | 55 | 40.8% |
| Engineering | 52 | 39.0% |
| Sales and Marketing | 27 | 20.2% |
Compare Septerna's department mix to industry peers.
See Full DataSepterna Employee Salary by Region (2026)
Septerna's average employee salary is $203,614 globally. Employees in North America receive the highest compensation.
Septerna median employee salary by region (USD)
| Region | Median Salary |
|---|---|
| North America | $160,000 |
Unlock salary by role, level, and city — and compare to Septerna's industry peers.
Unlock Salary DataSepterna Job Openings and Hiring Trends (2023-2026)
- Septerna had 16 active job postings in 2026, a 13.3% increase (+2) from 2025.
- Septerna had 14 active job postings in 2025, a 15.4% increase (+2) from 2024.
- Septerna had 12 active job postings in 2024, a 100.0% increase (+8) from 2023.
- Septerna had 4 active job postings in 2023, a 28.6% increase from 2022.
- Hiring velocity in 2026: 10 new roles/month, up from 8 in 2025 and 6 in 2024.
Septerna's hiring is accelerating: active job postings rose 13.3% in 2026 to 16, with new postings per month climbing from 4 in 2023 to 10 in 2026.
Track new postings per month, role-level demand, and hiring velocity vs. peers.
Unlock Hiring DataSepterna Employee Sentiment (2026)
Revelio Labs tracks employee sentiment across Septerna's workforce based on public professional data. Overall sentiment is positive and has held steady year over year in 2026.
Overall
Unlock the full sentiment breakdown by department, tenure, and trend over time.
Unlock SentimentSimilar Companies
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Frequently Asked Questions About Septerna
- How fast is Septerna growing?
- In 2026, Septerna's headcount grew 6.4% to 137 employees, up from 94 in 2025.
- See the full headcount history
- Where are Septerna employees located?
- Most Septerna employees are based in North America (98.2% of headcount), followed by Southern Europe.
- Explore where the workforce is based
- What is the average salary at Septerna?
- The average employee salary at Septerna is approximately $203.6k per year.
- Analyze the salary distribution
- How many new job postings does Septerna open per year?
- In Q1 2026, Septerna opened 31 new job postings. In 2025, Septerna opened 93 new job postings — about 8 per month.
- Track hiring trends by role
- When was Septerna founded and where is it headquartered?
- Septerna was founded in 2019 and is headquartered in South San Francisco, California.
- Compare Septerna to industry peers
Speak with a workforce expert about Septerna.
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