NASDAQ: LYEL

How many employees work at Lyell Immunopharma?

Lyell Immunopharma, Inc. (LYEL) has approximately 166 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Lyell Immunopharma’s total headcount has declined 45.6% from 305 employees in 2023 to 166 in 2026.

Data source: Revelio LabsCoverage: Global workforce, 20232026Published August 2026

Is Lyell Immunopharma hiring right now?

Yes, Lyell Immunopharma is actively hiring. Lyell Immunopharma had 15 active job postings in 2026, a 133.3% increase from 2025 see job openings & hiring trends.

About Lyell Immunopharma’s Workforce

Lyell Immunopharma, Inc. (LYEL) is a Biotech and Healthcare Services company that employs 166 people worldwide as of March 2026. It is the 9th-largest by headcount among its peers. Founded in 2018, the company is headquartered in South San Francisco, California and trades on the NASDAQ.

Lyell Immunopharma's workforce has declined 45.6% from 2023 to 2026, down 11.6% year over year in 2026. It fell to a low of 153 in 2025 Q3 before recovering. Its workforce is concentrated most in North America (97.9%), followed by Central and Western Asia (1.3%) and Southeast Asia (0.8%).

Lyell Immunopharma's functional groups are Finance and Operations (47.8%), Engineering (28.7%), and Sales and Marketing (23.5%), with Sales and Marketing growing fastest (up 9.3%). The average salary is $198,301, ranging from a median of $168,000 in North America to $86,000 in Central and Western Asia, up 7.4% year over year in 2026.

Lyell Immunopharma's active job postings rose 133.3% in 2026 to 15, with new postings per month cooling from 32 in 2023 to 9 in 2026. Overall employee sentiment is negative and declining.

Sourced from Revelio Labs workforce data.

Ticker
NASDAQ: LYEL
Headquarters
South San Francisco, California
Founded
2018
Industry
Biotech and Healthcare Services
Employees
166
YoY
-11.6% (-26)

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Lyell Immunopharma Annual Employee Count (2023-2026)

Interactive chart of Lyell Immunopharma annual worldwide employee count from 2023 to 2026.
  • Lyell Immunopharma had 166 employees in 2026, a 11.6% decline (-26) from 2025.
  • Lyell Immunopharma had 163 employees in 2025, a 21.4% decline (-65) from 2024.
  • Lyell Immunopharma had 228 employees in 2024, a 5.3% decline (-37) from 2023.
  • Lyell Immunopharma had 265 employees in 2023, a 14.3% decline (-15) from 2022.

Lyell Immunopharma's total workforce has grown from 153 employees in 2025 to 166 in 2026. Lyell Immunopharma's headcount peaked at 305 in 2023 before declining in 2025 and recovering through 2026.

Lyell Immunopharma, Inc. quarterly employee count

YearQtrEmployeesYoY ChangeYoY %
2026Q1166-26-11.6%
2025Q4163-65-21.4%
2025Q3153-102-26.4%
2025Q2164-99-25.0%
2025Q1192-68-15.7%
2024Q4228-37-5.3%
2024Q3255-47-13.3%
2024Q2263-42-12.0%
2024Q1260-39-15.0%
2023Q4265-15-14.3%
2023Q3302+32+0.1%
2023Q2305+50+1.0%

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Lyell Immunopharma Employee Count by Region (2026)

North America accounts for the largest share of Lyell Immunopharma's global workforce with approximately 98% of total employees, followed by Central and Western Asia and Southeast Asia.

Lyell Immunopharma employees by region

RegionEmployees% of Total
North America15997.9%
Central and Western Asia21.3%
Southeast Asia10.8%

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Lyell Immunopharma Employee Count by Department (2026)

Lyell Immunopharma's employee groups are Finance and Operations (47.8%), Engineering (28.7%), and Sales and Marketing (23.5%).

Lyell Immunopharma employees by department

DepartmentEmployees% of Total
Finance and Operations7947.8%
Engineering4728.7%
Sales and Marketing3923.5%

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Lyell Immunopharma Employee Salary by Region (2026)

Lyell Immunopharma's average employee salary is $198,301 globally. Employees in North America receive the highest compensation. Pay is lowest in Central and Western Asia, at a median of $86,000.

Lyell Immunopharma median employee salary by region (USD)

RegionMedian Salary
North America$168,000
Central and Western Asia$86,000

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Lyell Immunopharma Job Openings and Hiring Trends (2023-2026)

Interactive chart of Lyell Immunopharma annual active job postings from 2023 to 2026.
  • Lyell Immunopharma had 15 active job postings in 2026, a 133.3% increase (+3) from 2025.
  • Lyell Immunopharma had 12 active job postings in 2025, a 66.7% increase (+6) from 2024.
  • Lyell Immunopharma had 6 active job postings in 2024, a 111.1% decline (-15) from 2023.
  • Lyell Immunopharma had 21 active job postings in 2023, a 80.0% decline from 2022.
  • Hiring velocity in 2026: 9 new roles/month, up from 4 in 2025 and 12 in 2024.

Lyell Immunopharma's active job postings rose 133.3% in 2026 to 15, with new postings per month cooling from 32 in 2023 to 9 in 2026.

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Lyell Immunopharma Employee Sentiment (2026)

Revelio Labs tracks employee sentiment across Lyell Immunopharma's workforce based on public professional data. Overall sentiment is negative and has declined year over year in 2026.

Overall

NegativePositive

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Frequently Asked Questions About Lyell Immunopharma

How fast is Lyell Immunopharma growing?
In 2026, Lyell Immunopharma's headcount shrank 11.6% to 166 employees, down from 192 in 2025.
See the full headcount history
Where are Lyell Immunopharma employees located?
Most Lyell Immunopharma employees are based in North America (97.9% of headcount), followed by Central and Western Asia and Southeast Asia.
Explore where the workforce is based
What is the average salary at Lyell Immunopharma?
The average employee salary at Lyell Immunopharma is approximately $198.3k per year.
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How many new job postings does Lyell Immunopharma open per year?
In Q1 2026, Lyell Immunopharma opened 26 new job postings. In 2025, Lyell Immunopharma opened 52 new job postings — about 4 per month.
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When was Lyell Immunopharma founded and where is it headquartered?
Lyell Immunopharma was founded in 2018 and is headquartered in South San Francisco, California.
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