US OTC: LYRA

How many employees work at Lyra Therapeutics?

Lyra Therapeutics, Inc. (LYRA) has approximately 16 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Lyra Therapeutics’s total headcount has declined 69.0% from 51 employees in 2023 to 16 in 2026.

Data source: Revelio LabsCoverage: Global workforce, 20232026Published August 2026

Is Lyra Therapeutics hiring right now?

No, Lyra Therapeutics is not actively hiring. Lyra Therapeutics had 0 active job postings in 2026, a 0.0% no change from 2025 see job openings & hiring trends.

About Lyra Therapeutics’s Workforce

Lyra Therapeutics, Inc. (LYRA) is a Pharmaceuticals company that employs 16 people worldwide as of March 2026. It is the 8th-largest by headcount among its peers. Founded in 2005, the company is headquartered in Watertown, Massachusetts and trades on the US OTC.

Lyra Therapeutics's workforce has declined 69.0% from 2023 to 2026, down 39.3% year over year in 2026. It fell to a low of 16 in 2026 Q1 before recovering. Its workforce is concentrated most in North America (93.2%), followed by Sub-Saharan Africa (6.8%).

Lyra Therapeutics's functional groups are Finance and Operations (56.1%), Engineering (23.2%), and Sales and Marketing (20.7%). The average salary is $169,119, highest in North America at a median of $146,000.

Lyra Therapeutics's hiring activity held steady in 2026. Overall employee sentiment is positive and broadly stable.

Sourced from Revelio Labs workforce data.

Ticker
US OTC: LYRA
Headquarters
Watertown, Massachusetts
Founded
2005
Industry
Pharmaceuticals
Employees
16
YoY
-39.3% (-12)

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Lyra Therapeutics Annual Employee Count (2023-2026)

Interactive chart of Lyra Therapeutics annual worldwide employee count from 2023 to 2026.
  • Lyra Therapeutics had 16 employees in 2026, a 39.3% decline (-12) from 2025.
  • Lyra Therapeutics had 30 employees in 2025, a 10.3% increase (+2) from 2024.
  • Lyra Therapeutics had 28 employees in 2024, a 70.7% decline (-39) from 2023.
  • Lyra Therapeutics had 67 employees in 2023, a 12.9% increase (+21) from 2022.

Lyra Therapeutics's total workforce has declined from 51 employees in 2023 to 16 in 2026. Lyra Therapeutics's headcount peaked at 80 in 2024.

Lyra Therapeutics, Inc. quarterly employee count

YearQtrEmployeesYoY ChangeYoY %
2026Q116-12-39.3%
2025Q430+2+10.3%
2025Q331+1+11.8%
2025Q228-3+8.3%
2025Q128-52-62.0%
2024Q428-39-70.7%
2024Q330-25-68.8%
2024Q231-20-67.6%
2024Q180+33+12.7%
2023Q467+21+12.9%
2023Q355+11+3.0%
2023Q251+5-7.4%

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Lyra Therapeutics Employee Count by Region (2026)

North America accounts for the largest share of Lyra Therapeutics's global workforce with approximately 93% of total employees, followed by Sub-Saharan Africa.

Lyra Therapeutics employees by region

RegionEmployees% of Total
North America1593.2%
Sub-Saharan Africa16.8%

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Lyra Therapeutics Employee Count by Department (2026)

Lyra Therapeutics's employee groups are Finance and Operations (56.1%), Engineering (23.2%), and Sales and Marketing (20.7%).

Lyra Therapeutics employees by department

DepartmentEmployees% of Total
Finance and Operations956.1%
Engineering423.2%
Sales and Marketing320.7%

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Lyra Therapeutics Employee Salary by Region (2026)

Lyra Therapeutics's average employee salary is $169,119 globally. Employees in North America receive the highest compensation.

Lyra Therapeutics median employee salary by region (USD)

RegionMedian Salary
North America$146,000

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Lyra Therapeutics Job Openings and Hiring Trends (2023-2026)

Interactive chart of Lyra Therapeutics annual active job postings from 2023 to 2026.
  • Lyra Therapeutics had 0 active job postings in 2026, a 0% no change from 2025.
  • Lyra Therapeutics had 0 active job postings in 2025, a 0% no change from 2024.
  • Lyra Therapeutics had 0 active job postings in 2024, a 200.0% decline (-16) from 2023.
  • Lyra Therapeutics had 16 active job postings in 2023, a 90.9% increase from 2022.
  • Hiring velocity in 2026: 0 new roles/month, down from 1 in 2025 and 4 in 2024.

Lyra Therapeutics's hiring activity held steady in 2026.

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Lyra Therapeutics Employee Sentiment (2026)

Revelio Labs tracks employee sentiment across Lyra Therapeutics's workforce based on public professional data. Overall sentiment is positive and has held steady year over year in 2026.

Overall

NegativePositive

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Frequently Asked Questions About Lyra Therapeutics

How fast is Lyra Therapeutics growing?
In 2026, Lyra Therapeutics's headcount shrank 39.3% to 16 employees, down from 28 in 2025.
See the full headcount history
Where are Lyra Therapeutics employees located?
Most Lyra Therapeutics employees are based in North America (93.2% of headcount), followed by Sub-Saharan Africa.
Explore where the workforce is based
What is the average salary at Lyra Therapeutics?
The average employee salary at Lyra Therapeutics is approximately $169.1k per year.
Analyze the salary distribution
How many new job postings does Lyra Therapeutics open per year?
In Q1 2026, Lyra Therapeutics opened 0 new job postings. In 2025, Lyra Therapeutics opened 10 new job postings — about 1 per month.
Track hiring trends by role
When was Lyra Therapeutics founded and where is it headquartered?
Lyra Therapeutics was founded in 2005 and is headquartered in Watertown, Massachusetts.
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