How many employees work at Spyre Therapeutics LLC?
Spyre Therapeutics LLC has approximately 99 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Spyre Therapeutics LLC’s total headcount has grown 837.3% from 11 employees in 2023 to 99 in 2026.
Is Spyre Therapeutics LLC hiring right now?
Yes, Spyre Therapeutics LLC is actively hiring. Spyre Therapeutics LLC had 10 active job postings in 2026, a 66.7% decline from 2025 — see job openings & hiring trends.
About Spyre Therapeutics LLC’s Workforce
Spyre Therapeutics LLC is a Pharmaceuticals company that employs 99 people worldwide as of March 2026. It is the 6th-largest by headcount among its peers. Founded in 2013, the company is headquartered in Waltham, Massachusetts.
Spyre Therapeutics LLC's workforce has grown 837.3% from 2023 to 2026, up 3.4% year over year in 2026. Its workforce is concentrated most in North America (99.8%), followed by South America (0.2%).
Spyre Therapeutics LLC's functional groups are Finance and Operations (55.7%), Sales and Marketing (24.3%), and Engineering (20.0%), with Sales and Marketing growing fastest (up 25.3%). The average salary is $219,718, highest in North America at a median of $209,000, down 1.2% year over year in 2026.
Spyre Therapeutics LLC's active job postings fell 66.7% in 2026 to 10, with new postings per month climbing from 2 in 2023 to 11 in 2026. Overall employee sentiment is neutral but declining.
Sourced from Revelio Labs workforce data.
- Headquarters
- Waltham, Massachusetts
- Founded
- 2013
- Industry
- Pharmaceuticals
- Employees
- 99
- YoY
- +3.4% (+29)
As of March 2026
Spyre Therapeutics LLC workforce metrics
Unlock hiring rate, attrition rate, and 12 additional workforce metrics for Spyre Therapeutics LLC. Compare to peers, export the dataset, and access the full quarterly history.
Unlock MetricsSpyre Therapeutics LLC Annual Employee Count (2023-2026)
- Spyre Therapeutics LLC had 99 employees in 2026, a 3.4% increase (+29) from 2025.
- Spyre Therapeutics LLC had 92 employees in 2025, a 11.3% increase (+28) from 2024.
- Spyre Therapeutics LLC had 64 employees in 2024, a 13.1% increase (+34) from 2023.
- Spyre Therapeutics LLC had 30 employees in 2023, a 15.6% increase (+26) from 2022.
Spyre Therapeutics LLC's total workforce has grown from 11 employees in 2023 to 99 in 2026.
Spyre Therapeutics LLC quarterly employee count
| Year | Qtr | Employees | YoY Change | YoY % |
|---|---|---|---|---|
| 2026 | Q1 | 99 | +29 | +3.4% |
| 2025 | Q4 | 92 | +28 | +11.3% |
| 2025 | Q3 | 84 | +26 | +13.6% |
| 2025 | Q2 | 79 | +28 | +13.3% |
| 2025 | Q1 | 70 | +30 | +17.6% |
| 2024 | Q4 | 64 | +34 | +13.1% |
| 2024 | Q3 | 58 | +39 | +13.4% |
| 2024 | Q2 | 51 | +40 | +18.1% |
| 2024 | Q1 | 40 | +35 | +16.5% |
| 2023 | Q4 | 30 | +26 | +15.6% |
| 2023 | Q3 | 19 | +17 | +17.0% |
| 2023 | Q2 | 11 | +9 | +0.0% |
See Spyre Therapeutics LLC's complete headcount history, including quarterly breakdowns.
Get the DataSpyre Therapeutics LLC Employee Count by Region (2026)
North America accounts for the largest share of Spyre Therapeutics LLC's global workforce with approximately 100% of total employees, followed by South America.
Spyre Therapeutics LLC employees by region
| Region | Employees | % of Total |
|---|---|---|
| North America | 91 | 99.8% |
| South America | 0 | 0.2% |
Drill into city-level data, hiring trends by region, and historic geographic shifts.
Unlock Geographic DataSpyre Therapeutics LLC Employee Count by Department (2026)
Spyre Therapeutics LLC's employee groups are Finance and Operations (55.7%), Sales and Marketing (24.3%), and Engineering (20.0%).
Spyre Therapeutics LLC employees by department
| Department | Employees | % of Total |
|---|---|---|
| Finance and Operations | 55 | 55.7% |
| Sales and Marketing | 24 | 24.3% |
| Engineering | 20 | 20.0% |
Compare Spyre Therapeutics LLC's department mix to industry peers.
See Full DataSpyre Therapeutics LLC Employee Salary by Region (2026)
Spyre Therapeutics LLC's average employee salary is $219,718 globally. Employees in North America receive the highest compensation.
Spyre Therapeutics LLC median employee salary by region (USD)
| Region | Median Salary |
|---|---|
| North America | $209,000 |
Unlock salary by role, level, and city — and compare to Spyre Therapeutics LLC's industry peers.
Unlock Salary DataSpyre Therapeutics LLC Job Openings and Hiring Trends (2023-2026)
- Spyre Therapeutics LLC had 10 active job postings in 2026, a 66.7% decline (-3) from 2025.
- Spyre Therapeutics LLC had 13 active job postings in 2025, a 26.7% decline (-4) from 2024.
- Spyre Therapeutics LLC had 17 active job postings in 2024, a 177.8% increase (+16) from 2023.
- Spyre Therapeutics LLC had 1 active job postings in 2023, a 200.0% increase from 2022.
- Hiring velocity in 2026: 11 new roles/month, up from 11 in 2025 and 12 in 2024.
Spyre Therapeutics LLC's active job postings fell 66.7% in 2026 to 10, with new postings per month climbing from 2 in 2023 to 11 in 2026.
Track new postings per month, role-level demand, and hiring velocity vs. peers.
Unlock Hiring DataSpyre Therapeutics LLC Employee Sentiment (2026)
Revelio Labs tracks employee sentiment across Spyre Therapeutics LLC's workforce based on public professional data. Overall sentiment is neutral and has declined year over year in 2026.
Overall
Unlock the full sentiment breakdown by department, tenure, and trend over time.
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Frequently Asked Questions About Spyre Therapeutics LLC
- How fast is Spyre Therapeutics LLC growing?
- In 2026, Spyre Therapeutics LLC's headcount grew 3.4% to 99 employees, up from 70 in 2025.
- See the full headcount history
- Where are Spyre Therapeutics LLC employees located?
- Most Spyre Therapeutics LLC employees are based in North America (99.8% of headcount), followed by South America.
- Explore where the workforce is based
- What is the average salary at Spyre Therapeutics LLC?
- The average employee salary at Spyre Therapeutics LLC is approximately $219.7k per year.
- Analyze the salary distribution
- How many new job postings does Spyre Therapeutics LLC open per year?
- In Q1 2026, Spyre Therapeutics LLC opened 33 new job postings. In 2025, Spyre Therapeutics LLC opened 136 new job postings — about 11 per month.
- Track hiring trends by role
- When was Spyre Therapeutics LLC founded and where is it headquartered?
- Spyre Therapeutics LLC was founded in 2013 and is headquartered in Waltham, Massachusetts.
- Compare Spyre Therapeutics LLC to industry peers
Speak with a workforce expert about Spyre Therapeutics LLC.
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