How many employees work at Prime Medicine?
Prime Medicine, Inc. (PRME) has approximately 144 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Prime Medicine’s total headcount has declined 33.7% from 217 employees in 2023 to 144 in 2026.
Is Prime Medicine hiring right now?
Yes, Prime Medicine is actively hiring. Prime Medicine had 6 active job postings in 2026, a 40.0% decline from 2025 — see job openings & hiring trends.
About Prime Medicine’s Workforce
Prime Medicine, Inc. (PRME) is a Pharmaceuticals company that employs 144 people worldwide as of March 2026. It is the 4th-largest by headcount among its peers. Founded in 2019, the company is headquartered in Cambridge, Massachusetts and trades on the NASDAQ.
Prime Medicine's workforce has declined 33.7% from 2023 to 2026, down 26.8% year over year in 2026. It fell to a low of 144 in 2026 Q1 before recovering. Its workforce is concentrated most in North America (96.3%), followed by South Asia (2.0%) and Arab States (0.9%).
Prime Medicine's functional groups are Finance and Operations (51.1%), Engineering (36.5%), and Sales and Marketing (12.4%), with Finance and Operations growing fastest (up 2.4%). The average salary is $165,351, highest in North America at a median of $155,000, up 8.8% year over year in 2026.
Prime Medicine's active job postings fell 40.0% in 2026 to 6, with new postings per month cooling from 18 in 2023 to 1 in 2026. Overall employee sentiment is negative and declining.
Sourced from Revelio Labs workforce data.
- Ticker
- NASDAQ: PRME
- Headquarters
- Cambridge, Massachusetts
- Founded
- 2019
- Industry
- Pharmaceuticals
- Employees
- 144
- YoY
- -26.8% (-59)
As of March 2026
Prime Medicine workforce metrics
Unlock hiring rate, attrition rate, and 12 additional workforce metrics for Prime Medicine. Compare to peers, export the dataset, and access the full quarterly history.
Unlock MetricsPrime Medicine Annual Employee Count (2023-2026)
- Prime Medicine had 144 employees in 2026, a 26.8% decline (-59) from 2025.
- Prime Medicine had 146 employees in 2025, a 25.4% decline (-55) from 2024.
- Prime Medicine had 201 employees in 2024, a 5.7% decline (-25) from 2023.
- Prime Medicine had 226 employees in 2023, a 6.5% increase (+43) from 2022.
Prime Medicine's total workforce has declined from 217 employees in 2023 to 144 in 2026. Prime Medicine's headcount peaked at 231 in 2024.
Prime Medicine, Inc. quarterly employee count
| Year | Qtr | Employees | YoY Change | YoY % |
|---|---|---|---|---|
| 2026 | Q1 | 144 | -59 | -26.8% |
| 2025 | Q4 | 146 | -55 | -25.4% |
| 2025 | Q3 | 152 | -73 | -27.2% |
| 2025 | Q2 | 153 | -78 | -27.3% |
| 2025 | Q1 | 203 | -21 | -5.5% |
| 2024 | Q4 | 201 | -25 | -5.7% |
| 2024 | Q3 | 225 | +8 | +0.8% |
| 2024 | Q2 | 231 | +14 | +3.1% |
| 2024 | Q1 | 224 | +27 | +4.6% |
| 2023 | Q4 | 226 | +43 | +6.5% |
| 2023 | Q3 | 217 | +61 | +12.4% |
| 2023 | Q2 | 217 | +74 | +13.7% |
See Prime Medicine's complete headcount history, including quarterly breakdowns.
Get the DataPrime Medicine Employee Count by Region (2026)
North America accounts for the largest share of Prime Medicine's global workforce with approximately 96% of total employees, followed by South Asia and Arab States.
Prime Medicine employees by region
| Region | Employees | % of Total |
|---|---|---|
| North America | 138 | 96.3% |
| South Asia | 3 | 2.0% |
| Arab States | 1 | 0.9% |
| Sub-Saharan Africa | 1 | 0.7% |
Drill into city-level data, hiring trends by region, and historic geographic shifts.
Unlock Geographic DataPrime Medicine Employee Count by Department (2026)
Prime Medicine's employee groups are Finance and Operations (51.1%), Engineering (36.5%), and Sales and Marketing (12.4%).
Prime Medicine employees by department
| Department | Employees | % of Total |
|---|---|---|
| Finance and Operations | 74 | 51.1% |
| Engineering | 53 | 36.5% |
| Sales and Marketing | 18 | 12.4% |
Compare Prime Medicine's department mix to industry peers.
See Full DataPrime Medicine Employee Salary by Region (2026)
Prime Medicine's average employee salary is $165,351 globally. Employees in North America receive the highest compensation.
Prime Medicine median employee salary by region (USD)
| Region | Median Salary |
|---|---|
| North America | $155,000 |
Unlock salary by role, level, and city — and compare to Prime Medicine's industry peers.
Unlock Salary DataPrime Medicine Job Openings and Hiring Trends (2023-2026)
- Prime Medicine had 6 active job postings in 2026, a 40.0% decline (-2) from 2025.
- Prime Medicine had 8 active job postings in 2025, a 100.0% decline (-16) from 2024.
- Prime Medicine had 24 active job postings in 2024, a 120.0% increase (+18) from 2023.
- Prime Medicine had 6 active job postings in 2023, a 104.0% decline from 2022.
- Hiring velocity in 2026: 1 new roles/month, down from 4 in 2025 and 15 in 2024.
Prime Medicine's hiring is slowing: active job postings fell 40.0% in 2026 to 6, with new postings per month cooling from 18 in 2023 to 1 in 2026.
Track new postings per month, role-level demand, and hiring velocity vs. peers.
Unlock Hiring DataPrime Medicine Employee Sentiment (2026)
Revelio Labs tracks employee sentiment across Prime Medicine's workforce based on public professional data. Overall sentiment is negative and has declined year over year in 2026.
Overall
Unlock the full sentiment breakdown by department, tenure, and trend over time.
Unlock SentimentSimilar Companies
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Frequently Asked Questions About Prime Medicine
- How fast is Prime Medicine growing?
- In 2026, Prime Medicine's headcount shrank 26.8% to 144 employees, down from 203 in 2025.
- See the full headcount history
- Where are Prime Medicine employees located?
- Most Prime Medicine employees are based in North America (96.3% of headcount), followed by South Asia and Arab States.
- Explore where the workforce is based
- What is the average salary at Prime Medicine?
- The average employee salary at Prime Medicine is approximately $165.4k per year.
- Analyze the salary distribution
- How many new job postings does Prime Medicine open per year?
- In Q1 2026, Prime Medicine opened 4 new job postings. In 2025, Prime Medicine opened 52 new job postings — about 4 per month.
- Track hiring trends by role
- When was Prime Medicine founded and where is it headquartered?
- Prime Medicine was founded in 2019 and is headquartered in Cambridge, Massachusetts.
- Compare Prime Medicine to industry peers
Speak with a workforce expert about Prime Medicine.
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