NASDAQ: PRLD

How many employees work at Prelude Therapeutics?

Prelude Therapeutics, Inc. (PRLD) has approximately 74 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Prelude Therapeutics’s total headcount has declined 29.8% from 105 employees in 2023 to 74 in 2026.

Data source: Revelio LabsCoverage: Global workforce, 20232026Published August 2026

Is Prelude Therapeutics hiring right now?

No, Prelude Therapeutics is not actively hiring. Prelude Therapeutics had 0 active job postings in 2026, a 0.0% no change from 2025 see job openings & hiring trends.

About Prelude Therapeutics’s Workforce

Prelude Therapeutics, Inc. (PRLD) is a Pharmaceuticals company that employs 74 people worldwide as of March 2026. It is the 8th-largest by headcount among its peers. Founded in 2016, the company is headquartered in Wilmington, Delaware and trades on the NASDAQ.

Prelude Therapeutics's workforce has declined 29.8% from 2023 to 2026, down 11.6% year over year in 2026. It fell to a low of 74 in 2026 Q1 before recovering. Its workforce is concentrated most in North America (100.0%).

Prelude Therapeutics's functional groups are Finance and Operations (52.1%), Engineering (30.3%), and Sales and Marketing (17.6%). The average salary is $180,428, highest in North America at a median of $173,000, up 6.8% year over year in 2026.

Prelude Therapeutics's hiring activity held steady in 2026. Overall employee sentiment is neutral but declining.

Sourced from Revelio Labs workforce data.

Ticker
NASDAQ: PRLD
Headquarters
Wilmington, Delaware
Founded
2016
Industry
Pharmaceuticals
Employees
74
YoY
-11.6% (-29)

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Prelude Therapeutics Annual Employee Count (2023-2026)

Interactive chart of Prelude Therapeutics annual worldwide employee count from 2023 to 2026.
  • Prelude Therapeutics had 74 employees in 2026, a 11.6% decline (-29) from 2025.
  • Prelude Therapeutics had 79 employees in 2025, a 7.9% decline (-26) from 2024.
  • Prelude Therapeutics had 105 employees in 2024, a 2.1% increase (+3) from 2023.
  • Prelude Therapeutics had 102 employees in 2023, a 0.6% decline (+4) from 2022.

Prelude Therapeutics's total workforce has declined from 105 employees in 2023 to 74 in 2026. Prelude Therapeutics's headcount peaked at 113 in 2024.

Prelude Therapeutics, Inc. quarterly employee count

YearQtrEmployeesYoY ChangeYoY %
2026Q174-29-11.6%
2025Q479-26-7.9%
2025Q388-19-3.2%
2025Q299-14-4.5%
2025Q1103+1+1.5%
2024Q4105+3+2.1%
2024Q3107+5+0.7%
2024Q2113+8+1.0%
2024Q1102+1-0.9%
2023Q4102+4-0.6%
2023Q3102+11+0.8%
2023Q2105+16+2.7%

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Prelude Therapeutics Employee Count by Region (2026)

North America accounts for the largest share of Prelude Therapeutics's global workforce with approximately 100% of total employees.

Prelude Therapeutics employees by region

RegionEmployees% of Total
North America70100.0%

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Prelude Therapeutics Employee Count by Department (2026)

Prelude Therapeutics's employee groups are Finance and Operations (52.1%), Engineering (30.3%), and Sales and Marketing (17.6%).

Prelude Therapeutics employees by department

DepartmentEmployees% of Total
Finance and Operations3852.1%
Engineering2230.3%
Sales and Marketing1317.6%

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Prelude Therapeutics Employee Salary by Region (2026)

Prelude Therapeutics's average employee salary is $180,428 globally. Employees in North America receive the highest compensation.

Prelude Therapeutics median employee salary by region (USD)

RegionMedian Salary
North America$173,000

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Prelude Therapeutics Job Openings and Hiring Trends (2023-2026)

Interactive chart of Prelude Therapeutics annual active job postings from 2023 to 2026.
  • Prelude Therapeutics had 0 active job postings in 2026, a 0% no change from 2025.
  • Prelude Therapeutics had 0 active job postings in 2025, a 0% no change from 2024.
  • Prelude Therapeutics had 0 active job postings in 2024, a 200.0% decline (-6) from 2023.
  • Prelude Therapeutics had 6 active job postings in 2023, a 66.7% decline from 2022.
  • Hiring velocity in 2026: 0 new roles/month, up from 0 in 2025 and 2 in 2024.

Prelude Therapeutics's hiring activity held steady in 2026.

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Prelude Therapeutics Employee Sentiment (2026)

Revelio Labs tracks employee sentiment across Prelude Therapeutics's workforce based on public professional data. Overall sentiment is neutral and has declined year over year in 2026.

Overall

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Frequently Asked Questions About Prelude Therapeutics

How fast is Prelude Therapeutics growing?
In 2026, Prelude Therapeutics's headcount shrank 11.6% to 74 employees, down from 103 in 2025.
See the full headcount history
Where are Prelude Therapeutics employees located?
Most Prelude Therapeutics employees are based in North America (100.0% of headcount).
Explore where the workforce is based
What is the average salary at Prelude Therapeutics?
The average employee salary at Prelude Therapeutics is approximately $180.4k per year.
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How many new job postings does Prelude Therapeutics open per year?
In Q1 2026, Prelude Therapeutics opened 0 new job postings. In 2025, Prelude Therapeutics opened 0 new job postings — about 0 per month.
Track hiring trends by role
When was Prelude Therapeutics founded and where is it headquartered?
Prelude Therapeutics was founded in 2016 and is headquartered in Wilmington, Delaware.
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