How many employees work at Denali Therapeutics?
Denali Therapeutics, Inc. (DNLI) has approximately 529 total employees worldwide as of March 2026, according to Revelio Labs workforce intelligence data. Denali Therapeutics's total headcount has grown 14.9% from 460 employees in 2023 to 529 in 2026.
Data source: Revelio LabsCoverage: Global workforce, 2023–2026Published July 2026
Is Denali Therapeutics hiring right now?
Yes, Denali Therapeutics is actively hiring. Denali Therapeutics had 37 active job postings in 2026, a 42.6% decline from 2025 — see job openings & hiring trends.
About Denali Therapeutics's Workforce
Denali Therapeutics, Inc. (DNLI) is a Pharmaceuticals company that employs 529 people worldwide as of March 2026. It is the 8th-largest by headcount among its peers. Founded in 2013, the company is headquartered in San Francisco, California and trades on the NASDAQ.
Denali Therapeutics's workforce has grown 14.9% from 2023 to 2026, and is up 13.2% year over year in 2026. Its headcount fell to a low of 386 in 2024 Q2 before recovering, and it remains most concentrated in the United States (93.9%), with Switzerland (3.3%) and Canada (0.9%) next, while Australia is noted as its fastest-growing location.
Denali Therapeutics's largest groups by headcount are Finance and Operations (40.5%), Engineering (38.2%), and Sales and Marketing (21.3%), with Engineering also the fastest-growing at 5.9%. The average tenure is 2.4 years, and the average salary is $192,071, with regional medians of $251,000 in Western Europe and $173,000 in Northern America.
Denali Therapeutics's active job postings declined 42.6% in 2026 to 37, and new postings per month have cooled from 26 in 2023 to 16 in 2026. The sentiment across employees is neutral and has moved downward.
Sourced from Revelio Labs workforce data.
As of March 2026
Denali Therapeutics
workforce metrics
Headcount
529
13.2% YoY
Avg. Salary
$192.1k
1.4% YoY
Tenure
2.4yr
0.5yr YoY
Growth Rate
13.2%
3.0pts YoY
Hiring Rate
Attrition Rate
Unlock hiring rate, attrition rate, and 12 additional workforce metrics for Denali Therapeutics. Compare to peers, export the dataset, and access the full quarterly history.
- Denali Therapeutics had 529 employees in 2026, a 13.2% increase (+66) from 2025.
- Denali Therapeutics had 512 employees in 2025, a 17.0% increase (+80) from 2024.
- Denali Therapeutics had 432 employees in 2024, a 3.4% decline (-14) from 2023.
- Denali Therapeutics had 446 employees in 2023, a 0.4% decline (-2) from 2022.
Denali Therapeutics's total workforce has grown from 460 employees in 2023 to 529 in 2026.
Denali Therapeutics, Inc. — quarterly employee count (2023–2026)
| Year | Qtr | Employees | YoY Change | YoY % |
|---|---|---|---|---|
| 2026 | Q1 | 529 | +66 | +13.2% |
| 2025 | Q4 | 512 | +80 | +17.0% |
| 2025 | Q3 | 517 | +106 | +22.8% |
| 2025 | Q2 | 507 | +121 | +27.2% |
| 2025 | Q1 | 463 | +70 | +16.3% |
| 2024 | Q4 | 432 | -14 | -3.4% |
| 2024 | Q3 | 411 | -41 | -9.6% |
| 2024 | Q2 | 386 | -74 | -17.6% |
| 2024 | Q1 | 393 | -58 | -13.6% |
| 2023 | Q4 | 446 | -2 | -0.4% |
| 2023 | Q3 | 452 | +15 | +3.5% |
| 2023 | Q2 | 460 | +32 | +7.3% |
Want to see Denali Therapeutics's complete headcount history back to 2008, including quarterly breakdowns?
The United States accounts for the largest share of Denali Therapeutics's global workforce with approximately 94% of total employees, followed by Switzerland and Canada. Denali Therapeutics's headcount in Australia is growing fastest among its major locations, up 100.0% year over year in 2026.
Denali Therapeutics employees by country — 2026
| Country | Employees | % of Total | YoY % |
|---|---|---|---|
| United States | 498 | 93.9% | +1.9% |
| Switzerland | 18 | 3.3% | +22.3% |
| Canada | 5 | 0.9% | +29.5% |
| United Kingdom | 3 | 0.6% | +53.8% |
| India | 2 | 0.4% | +0.0% |
| Australia | 2 | 0.4% | +100.0% |
| Argentina | 1 | 0.2% | +0.0% |
| Germany | 1 | 0.1% | +0.0% |
| Italy | 1 | 0.1% | +0.0% |
| Turkey | 0 | 0.0% | +0.0% |
Drill into city-level data, hiring trends by region and historic geographic shifts
Denali Therapeutics's largest employee groups are Finance and Operations (40.5%), Engineering (38.2%), and Sales and Marketing (21.3%).
Denali Therapeutics employees by department — 2026
| Department | Employees | % of Total | YoY % |
|---|---|---|---|
| Finance and Operations | 219 | 40.5% | +0.5% |
| Engineering | 207 | 38.2% | +5.9% |
| Sales and Marketing | 115 | 21.3% | +3.5% |
Compare Denali Therapeutics's department mix to industry peers.
Denali Therapeutics's average employee salary is $192,071 globally. Employees in Western Europe receive the highest compensation, with median pay approximately 1.3x the global average. Pay is lowest in Northern America, at a median of $173,000.
Denali Therapeutics median employee salary by region — 2026 (USD)
| Region | Median Salary |
|---|---|
| Western Europe | $251,000 |
| Northern America | $173,000 |
Unlock salary by role, level, and city — and compare to Denali Therapeutics's industry peers.
- Denali Therapeutics had 37 active job postings in 2026, a 42.6% decline (+12) from 2025.
- Denali Therapeutics had 25 active job postings in 2025, a 64.9% decline (-24) from 2024.
- Denali Therapeutics had 49 active job postings in 2024, a 48.1% increase (+19) from 2023.
- Denali Therapeutics had 30 active job postings in 2023, a 82.4% decline from 2022.
- Hiring velocity in 2026: 16 new roles/month, up from 15 in 2025 and 18 in 2024. New metric
Denali Therapeutics's hiring is slowing: active job postings fell 42.6% in 2026 to 37, with new postings per month cooling from 26 in 2023 to 16 in 2026.
Track new postings per month, role-level demand, and hiring velocity vs. peers.
Revelio Labs tracks employee sentiment across Denali Therapeutics's workforce based on public professional data. Overall sentiment is neutral and has declined year over year in 2026.
Overall
Unlock the full sentiment breakdown by department, tenure, and trend over time.
Similar Pharmaceuticals Companies by Employee Count
- How fast is Denali Therapeutics growing?
- In 2026, Denali Therapeutics's headcount grew 13.2% to 529 employees, up from 463 in 2025.
- Where are Denali Therapeutics employees located?
- Most Denali Therapeutics employees are based in the United States (93.9% of headcount), followed by Switzerland and Canada.
- What is the average salary at Denali Therapeutics?
- The average employee salary at Denali Therapeutics is approximately $192.1k per year.
- How many people does Denali Therapeutics hire per year?
- In 2026, Denali Therapeutics opened roughly 192 new roles — about 16 per month.
- When was Denali Therapeutics founded and where is it headquartered?
- Denali Therapeutics was founded in 2013 and is headquartered in San Francisco, California.
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